Herpes viruses, cytokines, and altered hemostasis in vital exhaustion.

Seroepidemological Survey for Antibodies against Infectious Bovine Rhinotracheitis and Bovine Herpes 4 Viruses among Cattle in Different Provinces of Iran.

Symptomatic Reactivation of HSV Infection Correlates with Decreased Serum Levels of TNF-α

Background: Herpes simplex viruses (HSV) are human pathogens that establish lytic and latent infections. Reactivation from latency occurs intermittently, which represents a life-long source for recurrent infection. The role of immune factors in the control of recurrent symptomatic HSV lesions is complex and the exact role of cytokines remains unclear. Objective: To assess the levels of tumor ne...

Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection

The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. The antigenic volume imposed by persistent and latent viruses exposes the immune system to unique challenges that lead to host T-cell exhaustion, characterized...

A Review of the Classical and Molecular Diagnostic Methods of Herpes Simplex Virus

Human Herpes Viruses (HSV) contain eight pathogens. HSV is one of the most widespread viruses in the world and due to the simplicity of the way of transmission the number of people infected with the virus has increased in per year. The virus creates a wide range of diseases, including mucosal herpes infections and deadly herpes simplex encephalitis. Today, for the diagnosis of HSV infection se...

Sero-prevalence of Herpes Simplex and Epstein Barr Viruses in HIV positive patients in Tehran

Abstract Background and Aims: The burden of HIV infection and disease continues to be a major global public health concern all over the world. This study was conducted to measure IgG antibody against EBV viral capsid antigen (EBV-VCA IgG), Herpes Simplex Type1, and 2 to determine the seroprevalence of this infection in HIV-positive population. Materials and Methods: A Cross-sectional st...